Description
Gene Reports is a companion title to Gene and a member of the Gene Family. Gene Reports publishes papers that focus on the regulation, expression, function and evolution of genes in all biological contexts, including all prokaryotic and eukaryotic organisms, as well as viruses. Gene Reports strives to be a very diverse journal, and topics in all fields will be considered for publication (note that manuscripts on bioinformatics are only considered for review if they contain experiments). General topics include, but are not limited to, those that follow: Genome sciences – Focus on genomic DNA (chromosomal topology and organization, comparative genomics, DNA replication, DNA repair, mobile DNA, mitochondrial DNA, chloroplast DNA). Modern omics studies – Focus on the extraction of information from primary high-throughput datasets (e.g., DeepSeq, ChIP-Seq, Affymetrix microarrays, proteomics) that define gene regulatory circuitry, molecular pathways, and protein/protein networks, for the generation of testable hypotheses supported by experimental data. Gene regulation, expression, and function – Focus on processes that mediate gene read-out (epigenetics, chromatin, histone code, transcription, translation, protein degradation). Focus on functional RNAs (microRNAs, tRNAs, rRNAs, mRNA splicing, alternative polyadenylation). Cell signaling – Focus on the molecular mechanisms that transduce information from extra-cellular signaling (NF-kB, Wnt, Notch, TGFbeta/BMPs, FGFs, IGFs, etc.) or intracellular sensory (PAMPs, DAMPs, DNA, RNA sensing, etc.) cues to the nucleus for gene expression, with a special emphasis on physiological contexts, such as immunity, infectious disease, drug treatment, and cancers. Molecular pathology and regenerative medicine – Focus on the deregulation of molecular processes in human diseases and mechanisms supporting regeneration of tissues through pluripotent or multipotent stem cells. Genetics – Focus on development in model organisms (e.g., mouse, frog, fruit fly, worm), human genetic variation, and population genetics, as well as agricultural and veterinary genetics. Gene Reports encourages submission of novel manuscripts that present a reasonable level of analysis, functional relevance and/or mechanistic insight. Gene Reports also welcomes papers that have predominantly a descriptive component but improve the essential basis of knowledge for subsequent functional studies, or provide important confirmation of recently published discoveries. The primary criteria for acceptance are that the work is original and scientifically sound. The journal appreciates that standards of novelty are arbitrary, differ among disciplines and geographic locations, as well as change with time. In partnership with Editors, Referees and Authors, the journal will promote the revision of papers to ensure that accepted papers are reasonably complete and competitive with concurrent submissions in a given field. Authors are also welcome to submit to the other journals that make up the Gene Family: Gene, Meta Gene, Plant Gene.
