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MTP International Review of Science: Biochemistry Series One, Volume 4: Biochemistry of Lipids focuses on the processes, methodologies, reactions, and approaches involved in the biochemistry of lipids. The selection first elaborates on the enzymes of sterol biosynthesis and lipids in glycan biosynthesis. Topics cover polyprenols and glycan biosynthesis in green plants; polyprenols and glycan biosynthesis in yeasts and fungi; undecaprenol and bacterial wall glycan biosynthesis; methods of investigating particle-bound enzymes of sterol biosynthesis; and relationship of the multi-enzymic synthesis of cholesterol to other microsomal processes. The text then elaborates on the biosynthesis of saturated fatty acids, dynamic role of lipids in the nervous system, and biosynthesis of unsaturated fatty acids. Discussions focus on anaerobic pathway of monoenoic fatty acid biosynthesis, exchange of brain lipids, lipids and transmission in the nervous system, fatty acid synthetase, and lipid distribution within the nervous system. The manuscript examines halogenated sulphatides and prostaglandins, including identification of prostaglandins in organs and body fluids, estimation of prostaglandins, and occurrence of halosulphatides in membranes. The selection is a valuable reference for researchers interested in the biochemistry of lipids.

“Research on the biochemistry and molecular biology of lipids and lipoproteins has experienced remarkable growth in the past 20 years, particularly with the realization that many different classes of lipids play fundamental roles in diseases such as heart disease, obesity, diabetes, cancer and neurodegenerative disorders. The 5th edition of this book has been written with two major objectives. The first objective is to provide students and teachers with an advanced up-to-date textbook covering the major areas of current interest in the lipid field. The chapters are written for students and researchers familiar with the general concepts of lipid metabolism but who wish to expand their knowledge in this area. The second objective is to provide a text for scientists who are about to enter the field of lipids, lipoproteins and membranes and who wish to learn more about this area of research. All of the chapters have been extensively updated since the 4th edition appeared in 2002. Key Features. Represents a bridge between the superficial coverage of the lipid field found in basic biochemistry text books and the highly specialized material contained in scientific review articles and monographs. Allows scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances. Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry”

Biochemistry of milk products documents advances in the field and focuses on the two most active areas of research areas, which are starter cultures and enzymes for use in cheese and other foods, and factors influencing the functional properties of milk.The book covers the current thinking and research on the roles of proteinases and peptidases in the milk clotting process and in texture and flavour development during maturation of product. It also covers the protein engineering of enzymes and molecular biological manipulation of microorganisms, including the use of protein engineering to clarify the molecular basis of functional behavior and to manipulate protein properties in a defined and planned way.Biochemistry of milk products provides important reading for research workers, lecturers, graduates and final year undergraduates with interest in the practical applications of molecular biology, enzymology, and protein chemistry, not just in improving the quality and performance of dairy foods and ingredients but also in a much wider context.

Biochemistry of Parasites, Second Edition presents the biochemical aspects of parasitology. The topics covered in the book include inorganic substances; carbohydrate relationships of parasites; parasitic metabolism of carbohydrates and transport mechanisms; distribution of lipids in the bodies of parasites; and disturbances in the host’s protein metabolism during parasitic infections. Parasitologists and biochemists will find the book interesting.

Biochemistry of Taste and Olfaction examines the biochemical aspects of taste and olfaction and their relevance to nutrition, medicine, and food science. More specifically, it considers the biological processes that influence dietary habits, nutritional status, and enjoyment of food, as well as other important social and biological phenomena. It also describes biochemical mechanisms at the peripheral receptor level in taste and olfaction, with emphasis on the role of the cell surface, along with neurotransmitters and other neurochemical aspects of the olfactory system. Organized into five sections comprised of 24 chapters, this book begins with an overview of biochemical approaches used in studying the phenomena of taste and olfaction. It then proceeds with a discussion of olfactory receptor mechanisms, the accessibility of odorant molecules to the receptors, the role of cilia in olfactory recognition, and the involvement of receptor proteins in vertebrate olfaction. Middle chapters focus on the chemosensation, major histocompatibility complex and olfactory receptors, taste receptor mechanisms, biochemistry of sugar reception in insects, intensity/time phenomena in sugar sweetness, and recognition of taste stimuli at the initial binding interaction. The reader is also introduced to the physicochemical principles of taste and olfaction, molecular mechanisms of transduction in chemoreception, biochemical mechanisms in vertebrate primary olfactory neurons, neurotransmitter biochemistry of the mammalian olfactory bulb, and chemical sensing by bacteria. Examples of chemical sensory systems are included. This book will be of interest to biochemists, physiologists, neurobiologists, neuroscientists, molecular biologists, food scientists, students, and specialists in psychology, neurophysiology, organic chemistry, and nutrition.

Biochemistry of the Amino Acids, Second Edition, Volume II focuses on the trends in research on amino acids and biochemistry. Given considerations are incorporation of amino acids into proteins, amino acid sequences, and discovery of amino acids. The first part of the book deals with intermediary metabolism of amino acids. Particularly noted are alanine, aspartic, adenylosuccinic, hydroxyaspartic acids, and asparagine. The book also has discussions on glutamic acid, glutamine, glycine, serine, and sarcosine. The processes and syntheses involved in these acids are noted. Another part of the book focuses on the formation, degradation, reactions, and conversion of acids. The processes and experiments discussed are supported by numerical analysis, and the biosynthesis of acids in microorganisms is also considered. The book also notes some disorders of amino acid metabolism in humans. These disorders include cystinuria, glycinuria, ammonemia, prolinemia, maple syrup urine disease, and homocystinuria. Discussions focus on how these diseases develop and the symptoms associated with them. The book is a vital source of data for readers interested in the study of amino acids.

Biochemistry of Thermophily covers the proceedings of a seminar held under the auspices of the U.S.-Japan Cooperative Science Program at the East-West Center in Honolulu, Hawaii on June 22-24, 1977. This seminar focuses on biochemistry of thermophilic microorganisms. It presents an achievement in the complex field of thermophiles and their unique properties. This book discusses the fatty acid composition in several strains of moderately and extremely thermophilic bacteria, the membrane and lipid components, the biosynthesis and function of -cyclohexyl fatty acids, and the influence of growth temperature and lipid state on lipid and protein distribution. It then presents the ecologic and genetic aspects of thermophilic bacteria, including their morphology, surface structure, and transfection. It also examines the function and thermostability of ribosomal proteins, polypeptides, and polyamines in thermophilic bacteria. Finally, the book discusses the thermostability of proteins, the effect of amino acid substitution on conformational stability of thermophile, the thermophilic enzymes, and the physiology of thermophilic bacteria. This book will be helpful to molecular and research biologists, teachers, and students who wish to expand their understanding on mechanisms of thermophilicity, thermostability, and thermophilic microorganisms.

Biochemistry of Vision provides information pertinent to vision biochemistry. This book discusses the biochemical information derived primarily from studies on nonocular tissues and describes the biochemical reactions related to the function of the retina and pigmented epithelium. Organized into 16 chapters, this book begins with an overview of the visual system and the structure of the vertebrate eye. The text then proceeds with a discussion of photoreceptor, which has a highly membranous structure. Other chapters cover a brief discussion of several topics, including biomembranes, photochemistry, spectral properties of retinal isomers, and the photochemical properties of the chromophore of rhodopsin. This book discusses as well the properties and intramembrane disposition of rhodopsin. The final chapter deals with the biochemistry of photoreceptor disorders and summarizes the basic knowledge on neurotransmitters and electrophysiology in the retina. This book is intended for ophthalmologists and medical students who are interested in the molecular aspects of photoreceptor diseases.

Biochemistry: The Chemical Reactions of Living Cells is a 16-chapter reference source on chemical structures and reactions of living cells. The first three chapters of this book contain introductory material on cell structure, molecular architecture, and energetic. The subsequent chapters examine the allosteric effect of the binding structures of oligomeric enzymes, microtubules, viruses, and muscle. These chapters also describe the structures and chemical properties of membranes and of the surrounding cell coats. The discussions then shift to the general properties of enzymes, the kinetics of chemical reactions, and the various mechanisms employed in enzymatic catalysis. Considerable chapters are devoted to the reaction sequences found in metabolism. These chapters particularly examine the carbohydrate and lipid metabolism; photosynthesis; and biosynthesis and catabolism of an enormous number of nitrogenous compounds. The final chapters highlight the genetic and hormonal control of metabolism, development, and brain function. Biochemistry teachers and students will find this book of great value.

The underlying theme of this volume is the understanding of the molecules and processes important in the primary metabolism of insects. The 19 chapters provide both rich historical perspectives and timely reviews of current research, as well as showing the extent of progress to be expected in the near future, including the application of advanced techniques now used for the study of microbial and mammalian processes. The major themes of metabolism, proteins and nucleic acids, and biochemical events in the nervous system each have several chapters devoted to them, but specific topics such as pigments, toxins, and aging are also covered in detail. This extensive volume is therefore an invaluable source of information not only for entomologists but also for all scientists whose work involves insect biochemistry, including zoologists, biochemists, and molecular biologists and geneticists.

Chemistry, Biochemistry, and Pharmacological Activity of Prostanoids contains the proceedings of a symposium on the Chemistry and Biochemistry of Prostanoids held at the University of Salford, England on July 10-14, 1978. Separating 29 papers of the symposium as chapters, this book begins with a description of prostanoids in health and disease and recent developments in the synthesis of antisecretory prostaglandins. Other topics discuss synthesis of some novel 11-deoxyprostaglandins; bicycles, tricycles and prostaglandin synthesis; chemical and biological studies on new prostanoids; and isolation and characterization of enzymes involved in prostaglandin biosynthesis. Structure activity relationships of prostaglandins and a biochemical background of caloric restriction therapy of obesity are also explained.

“Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides presents a comprehensive, systematic and authoritative survey of information about a family of chemically related, but functionally diverse, naturally occurring polysaccharides–the (1-3)-glucans. International contributors describe the chemical and physicochemical properties of these glucans and their derivatives and the molecular biological and structural aspects of the enzymes involved in their formation and breakdown. A detailed analysis of their physiological roles in the various biological situations in which they are found will be provided. Additionally, evolutionary relationships among the family of these glucans will be described. Key Features. Topics of medical relevance include detailing the glucans’ interactions with the immune system and research for cancer therapy applications. Web resource links allow scientists to explore additional beta glucan research. Separate indexes divided into Species and Subject for enhanced searchability”

Clinical Biochemistry: Contemporary Theories and Techniques, Volume 3 broadens the scope of clinical biochemistry, discussing relevant aspects of serology, microbiology, monoclonal antibody techniques, and instrumentation. This volume includes the biochemical monitoring of cancer, use of chemical and physiochemical approaches to detecting and identifying etiological agents in clinical specimens, and monoclonal antibodies in clinical investigations. The serologic methods in disease diagnosis, instrumentation in clinical chemistry, and hemoglobin analysis and hemoglobinopathies are also deliberated. This text likewise covers the conventional microbiological techniques, serology of streptococcal infections, and impact of microprocessors on clinical instrumentation. This book is a good reference for clinicians interested in theories and techniques related to clinical biochemistry.

Comparative Biochemistry of Parasites contains the proceedings of an international symposium organized by the Janssen Research Foundation and held at Janssen Pharmaceutica in Belgium on September 1-3, 1971. The symposium reviewed progress in the understanding of the physiology and biochemistry of parasites such as protozoa and helminths. Organized into 34 chapters, this volume begins with an overview of early research on parasite biochemistry before turning to a discussion of antischistosomal drugs and their biochemical effects on parasites. The reader is then introduced to the biochemistry of carbohydrates in nematodes and cestodes; neurotransmitters in trematodes; pharmacological aspects and biochemical effects of tetramisole; the mechanism of action of berenil (Diminazene) and related compounds; and dihydrofolate reductases in parasitic protozoa and helminths. Other chapters focus on the loss of fatty acid biosynthesis in flatworms, the cytochrome system in Kinetoplastidae, oxidative phosphorylation in Moniezia mitochondria, and the role of non-heme iron in cestode respiration. Scientists, particularly physiologists and biochemists, will find this book an invaluable source of information on parasite physiology and biochemistry.

Comparative Biochemistry: A Comprehensive Treatise, Volume III: Constituents of Life Part A focuses on the processes, methodologies, and mechanisms involved in the biological transformations of matter. Composed of contributions of authors, the book first gives emphasis to the comparative features of fatty acid occurrence and distribution. The formation of fatty acids and lipids in living organisms; naturally occurring fatty acids and lipids; relationship between types and distribution of fatty acids and their biological origin are considered. The text also looks at the structure and distribution of sterols, steroid metabolism of lipids, and the distribution and metabolism of phospholipids. The book focuses as well on the structure and occurrence of natural monosaccharides and oligosaccharides. The occurrence of commoner monosaccharides and oligosaccharides; the compositions, reactions, and characteristics of nucleosides, nucleotides, and nucleic acids; and chromatographic examinations of biological materials for free sugars are considered. The text also looks at the structure, metabolism, and distribution of terpenoids and quinones. The book is a vital source of information for readers wanting to study the processes, methodologies, and mechanisms involved in the biological transformation of matter.

Comparative Biochemistry: A Comprehensive Treatise, Volume IV: Constituents of Life Part B focuses on the distribution, biogenesis, and metabolism of cells and organisms. Composed of various literature, the book first looks at the optical asymmetry of metabolites. The natural occurrence of D-amino acids and L-sugars; significance of purity; optical asymmetry and protein structure; and the relationship of optical asymmetry and cancer are discussed. The text also discusses structural studies on cellulose, starch, and glycogen; biochemistry of lignin formation; structure and localization of nucleic acids; and intraspecific and interspecific variations of protein molecules. The book considers the metabolism of aromatic amino acids, structural and chemical properties of keratin-forming tissues, sclerotization, and blood coagulation. The text further discusses metamorphosis and biochemical adaptation in amphibians. The importance of intrinsic tissue sensitivity in tadpoles; comparative morphological alterations; and the increase in serum albumin and serum protein are considered. The book focuses as well on the structure, distribution, and metabolism of porphyrins, pteridines, and carotenoids. The selection is a good source of data for researchers wanting to study the distribution, biogenesis, and metabolism of cells and organisms.