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Nonhuman Primates in Biomedical Research: Biology and Management represents the most comprehensive publication of its type on nonhuman primates. It also provides basic information on the biology and management of primates for anyone responsible for the care and use of these animals. A related book on primate diseases will be published in 1996.

This volume and its companionNonhuman Primates in Biomedical Research: Biology and Managementrepresent the most comprehensive publications of their type on nonhuman primates. This volume addresses the diseases of nonhuman primates with an emphasis on the etiological factors, clinical signs, diagnostic pathology, therapy, and management. Its companion volume serves as a general reference for those who provide care for these animals and for those who use them in biomedical research.

"Nutritional Composition of Fruit Cultivars provides readers with the latest information on the health related properties of foods, making the documentation of the nutritive value of historical cultivars especially urgent, especially before they are lost and can't be effectively compared to modern cultivars. Because there is considerable diversity and a substantial body of the compositional studies directed towards commercial varieties, this information is useful for identifying traits and features that may be transposed from one variety to another. In addition, compositional and sensory features may also be used for commercialization and to characterize adulteration. Detailed characterization of cultivars can be used to identify ""super-foods"". Alternatively, unmasked historical cultivars may be the focus of reinvigorated commercial practices. Each chapter in this book has sections on the botanical aspects, the composition of traditional or ancient cultivars, the composition of modern cultivars, a focus on areas of research, the specialty of the communicating author of each chapter, and summary points. Key Features. Presents the botanical aspects and composition of both traditional and modern plants, including in-depth insight into current research, and overall summary points for each fruit for consistent comparison and ease of reference. Provides important information in the consideration of preservation, transference, or re-introduction of historical/traditional cultivars into current crop science. Provides details on compositional and sensory parameters, from aroma and taste to micro- and macronutrients. Includes data on nutraceuticals and novel components that have proven to impact on, or be important in, food quality, storage, processing, storage, and marketing"

Organization and Assembly of Plant and Animal Extracellular Matrix presents a state-of-the-art view of some of the experimental systems in plant and animal matrix biology. It discusses certain principles underlying establishment of complex three-dimensional architecture cross broad evolutionary boundaries. The opening chapter reviews studies on the cellular mechanisms responsible for storage, release, assembly, and function of extracellular matrices during early sea urchin development. The subsequent chapters describe the structure, assembly, disassembly, and molecular biology of the Chlamydomonas reinhardtii cell wall. The chapters also summarize the status of work on basement membrane assembly. Important insights into approaches to identify critical molecular domains and the complexity of relating defined molecular associations to establishment of matrix architecture are provided. A family of discovered cell wall genes that encode protein products containing up to 70% glycine is presented in Chapter 4. This is followed by a discussion on the role of alginate self-assembly in cell wall formation in Fucus. The book goes on to address the issue of protein-carbohydrate recognition with a detailed discussion of plant and animal lectins. Chapter 7 tackles a family of genes encoding higher plant hydroxyproline-rich glycoproteins (HRGPs) and the relationship between the HRGP genes cloned and their products. The final two chapters are devoted to one of the most important classes of protein modifying enzymes for extracellular matrix formation and function, the prolyl hydroxylases. This book will be of help to workers in plant and animal matrix in understanding information, approaches, and ideas that they may not normally encounter.

"With contributions that review research on this topic throughout the world, Oxidative Damage to Plants covers key areas of discovery, from the generation of reactive oxygen species (ROSs), their mechanisms, quenching of these ROSs through enzymatic and non-enzymatic antioxidants, and detailed aspects of such antioxidants as SOD and CAT. Environmental stress is responsible for the generation of oxidative stress, which causes oxidative damage to biomolecules and hence reduces crop yield. To cope up with these problems, scientists have to fully understand the generation of reactive oxygen species, its impact on plants and how plants will be able to withstand these stresses. Key Features. Provides invaluable information about the role of antioxidants in alleviating oxidative stress. Examines both the negative effects (senescence, impaired photosynthesis and necrosis) and positive effects (crucial role that superoxide plays against invading microbes) of ROS on plants. Features contributors from a variety of regions globally"

Oxygen in the Animal Organism is a compilation of papers presented during the symposium on Oxygen in the Animal Organism, jointly sponsored by the International Union of Biochemistry and the International Union of Physiological Sciences, held at Bedford College, London in September 1963. The book provides a multidisciplinary approach to the study of the subject of oxygen in the animal organism. The papers presented cover a wide range of facts and hypotheses on the subject. Topics discussed include studies in the transport of oxygen; the fundamental physics and chemistry of oxygen; the diffusion of oxygen from the capillaries to the mitochondria; the neural and humoral components to the regulation of ventilation; and the evolution of biochemical pathways for oxygen. Biologists, biochemists, biophysicists, physiologists, and researchers will find the text informative and insightful.

Pathology of Domestic Animals, Volume 1 elaborates on the bone structure and diseases, as well as the genital, circulatory, and respiratory systems, of domestic animals. The manuscript first offers information on bones, joints, and synovial structures and diseases of joints, including adaptational deformities of the skeleton, metabolic diseases of bones, necrosis and inflammation of bones, and discontinuities of bone and the healing of fractures. The text then ponders on the circulatory and respiratory systems. Discussions focus on congenital anomalies of the heart and large vessels, myocardium, hypertrophy and dilation of the heart, pharynx and guttural pouches, larynx and trachea, lungs, and pleura and mediastinum. The publication examines the haemopoietic system and endocrine glands. Topics include blood and bone marrow, general reactions of erythrocytes to injury, lymphoreticular tissues, adrenal glands and paraganglia, and polycythaemia. The book then reviews the male and female genital systems. The manuscript is a valuable source of data for readers interested in the pathology of domestic animals.

"Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity. This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful. Key Features. Focuses on the personalized management of immunosuppression therapy in individual transplant patients. Presents information that applies to many areas, including gmass spectrometry, assay design, assay validation, clinical chemistry, and clinical pathology. Provides practical guidelines for the initial selection and subsequent modifications of immunosuppression therapy in individual transplant patients. Reviews the latest research in biomarker monitoring in personalizing immunosuppressant therapy, including potential new markers not currently used, but with great potential for future use. Explains how monitoring graft-derived, circulating, cell free DNA has shown promise in the early detection of transplant injury in liquid biopsy"